Research Spotlight

Posted July 15th 2016

The harder one looks, the more one finds.

Michael J. Mack M.D.

Michael J. Mack M.D.

Mack, M. J. (2016). “The harder one looks, the more one finds.” J Thorac Cardiovasc Surg 152(1): 5-6.

Full text of this article.

The article by Gleason and colleagues in this issue of the Journal reports the risk and extent of neurologic injury in high risk patients with aortic stenosis undergoing either transcatheter aortic valve replacement (TAVR) or surgical aortic valve replacement (SAVR). The study reports the rate of stroke at 30 days, 1 year, and 2 years postprocedure in the 750 patients enrolled in the Corevalve High-Risk Study. They found no difference in stroke between the TAVR and SAVR groups at 30 days and 1 year, but a higher incidence of stroke at 2 years in the group undergoing SAVR.


Posted July 15th 2016

Presentation of the Julius M. Friedenwald Medal to C. Richard Boland, M.D., A.G.A.F.

Ajay Goel Ph.D.

Ajay Goel Ph.D.

Carethers, J. M. and A. Goel (2016). “Presentation of the Julius M. Friedenwald Medal to C. Richard Boland, M.D., A.G.A.F.” Gastroenterology 150(7): 1673-1677.

Full text of this article.

We are extremely delighted and thrilled that the American Gastroenterological Association (AGA) Institute chose to bestow C. Richard Boland with the Julius M. Friedenwald Medal during Digestive Disease Week in San Diego, California, in May 2016. As the singular highest honor given to any AGA member, the award was established in 1941 and recognizes “an individual who has contributed significantly to the AGA and has made lifelong contributions to the field of gastroenterology.” Rick fits that description aptly not only for his groundbreaking and world-renowned research contributions to the greater understanding of the field of heritable colorectal cancer, which were largely shaped by his own family’s exposure to a devastating cancer syndrome, but also for his stellar leadership of 2 separate gastroenterology divisions and the AGA Institute. An additional dimension of his contributions to the field of gastroenterology is the multitude of trainees Rick has mentored that have furthered his and other research in the field of gastroenterology, from which both of the authors have greatly benefited, and which has led to the development of many into leaders within gastroenterology.


Posted July 15th 2016

Lesion-specific factors contributing to inhospital costs in adults with congenital heart disease.

Ari M. Cedars M.D.

Ari M. Cedars M.D.

Cedars, A. M., S. Burns, E. L. Novak and A. P. Amin (2016). “Lesion-specific factors contributing to inhospital costs in adults with congenital heart disease.” Am J Cardiol 117(11): 1821-1825.

Full text of this article.

The population of adults with congenital heart disease (ACHD) in the United States is growing rapidly with concomitant increases in care costs. We sought to define the variables having the greatest influence on annual cost of inpatient care in patients with ACHD in the United States. To do so, we conducted a retrospective analysis of admissions in patients >18 years old with a 3-digit International Classification of Disease, Ninth Revision, code of 745 to 747 from the State Inpatient Databases of Arkansas (2008 to 2010), California (2003 to 2012), Florida (2005 to 2012), Hawaii (2006 to 2010), Nebraska (2003 to 2011), and New York (2005 to 2012). We selected variables we believed would have the greatest effect on care costs and built a series of multivariable regression models grouping patients by congenital lesion to examine the relative contribution of the specified variables to total annual inpatient cost. We analyzed a total of 68,314 patients aged 57 +/- 18.6 years, 51% of whom were women. The multivariable regression model had an overall R(2) of 0.35. Readmission was responsible for 10.3% of annual inpatient cost among all patients with ACHD and had the greatest effect on inpatient care cost for each congenital lesion except Eisenmenger syndrome and conotruncal abnormalities, for both of which it was the second most significant contributor. Other major contributors to annual inpatient care costs included length of stay and operative procedures. In conclusion, rehospitalization is the most significant contributor to annual inpatient cost for individual patients with ACHD in the United States, regardless of underlying anatomy.


Posted July 15th 2016

Books in Cardiovascular Disease Received in 2015 and Early 2016.

William C. Roberts M.D.

William C. Roberts M.D.

Roberts, W. C. (2016). “Books in cardiovascular disease received in 2015 and early 2016.” Am J Cardiol 118(1): 149-152.

Full text of this article.

The Good Books from the editor columns were initially published in 1986 and have appeared annually since that time. In 1985, a total of 16 books were received and discussed in the 1986 column. As shown in the accompanying figure (Figure 1), the number of books received rose to a peak in 1993 when 81 books were received and reviewed in the 1994 column. Since that time the number of books received yearly has slowly but steadily decreased such that in 2015 only 22 books were received and all were commented on. It appears that the number of medical books published yearly is decreasing, and publishers apparently are not sending out copies of the books published to medical journals for review. Although I love books, I now often go initially to Google for medical information and then to books and journals.


Posted July 15th 2016

Proceedings of the Editorial Board Meeting of The American Journal of Cardiology on April 3, 2016.

William C. Roberts M.D.

William C. Roberts M.D.

Roberts, W. C. (2016). “Proceedings of the editorial board meeting of the American journal of cardiology on April 3, 2016.” Am J Cardiol 118(1): 153-154.

Full text of this article.

The annual editorial board meeting of The American Journal of Cardiology (AJC) was held on April 3, 2016, at the time of the Annual Scientific Sessions of the American College of Cardiology. The major purpose of the meeting is to thank the editorial board members for their considerable help during the previous year in reviewing manuscripts and to seek their suggestions for improving the journal. The meeting began with a discussion by the publisher, Ms. Joan Anuels, who described several initiatives that Elsevier has introduced during the past year for many of the journals, including the AJC.