Periarterial papaverine to treat renal artery vasospasm during robot-assisted laparoscopic partial nephrectomy.

Sharnae Stevens Pharm.D.
Sorokin, I., S. L. Stevens and J. A. Cadeddu (2018). “Periarterial papaverine to treat renal artery vasospasm during robot-assisted laparoscopic partial nephrectomy.” J Robot Surg 12(1): 189-191.
Renal artery vasospasm can be a troublesome complication during robot-assisted laparoscopic partial nephrectomy. Urologists performing this procedure, especially if utilizing selective arterial vascular microdissection, should be aware of using papaverine for both prevention and treatment of renal artery vasospasm. We present a 33-year-old male who developed severe renal artery vasospasm just with hilar dissection causing the kidney to become ischemic. Papaverine was topically applied on the renal arteries resulting in vasodilation and reperfusion of the kidney. Our objective of this report is to raise awareness of this complication as well as to review the literature on periarterial papaverine use and the dosing for topical applications.