Research Spotlight

Baylor Health Sciences Library brings to you each month the latest published research from the Baylor Scott & White and Texas A&M College of Dentistry communities. Each newly published article features the researcher, the abstract, and link to the full text. For information on including your own research, please contact Sudha Ramakrishnan at Sudha.Ramakrishnan@BSWHealth.org for BSWH or at sudharamakrishnan@tamu.edu for COD.


Posted March 16th 2021

Do We Really Need to Worry About Calcaneocuboid Subluxation During Lateral Column Lengthening for Planovalgus Foot Deformity?

Jacob R. Zide M.D.

Jacob R. Zide M.D.

Siebert, M., Hedrick, B.N., Zide, J.R., Thomas, D.M., Shivers, C., Pierce, W.A., Kanaan, Y., Harris, M.C. and Riccio, A.I. (2021). “Do We Really Need to Worry About Calcaneocuboid Subluxation During Lateral Column Lengthening for Planovalgus Foot Deformity?” J Pediatr Orthop 41(3): e246-e251.

Full text of this article.

BACKGROUND: Although lengthening of the lateral column through an osteotomy of the anterior calcaneus is an integral component of flatfoot reconstruction in younger patients with flexible planovalgus deformities, the procedure has been implicated in iatrogenic calcaneocuboid (CC) subluxation and subsequent degenerative changes at the CC articulation. The purpose of this study is to characterize alterations at the CC joint after lateral column lengthening (LCL) and determine if Steinmann pin stabilization of the CC joint before distraction maintains a normal relationship. METHODS: Seven matched pairs of fresh-frozen cadaveric feet underwent preprocedure plain radiography and cross-sectional computed tomography (CT) imaging. LCL by osteotomy through the anterior calcaneus was then performed. One foot of each matched pair had a single smooth Steinmann pin placed centrally across the CC joint before osteotomy distraction. Distraction across each osteotomy was then performed and maintained with a 12-mm porous titanium wedge. Repeat imaging was obtained and compared with preprocedure studies to quantify sagittal and rotational differences at the CC articulation. RESULTS: Following LCL, plain radiography demonstrated statistically significant increases in the percentage of the calcaneal articular surface dorsal to the superior aspect of the cuboid in both the pinned (8.2% vs. 17.6%, P=0.02) and unpinned (12.5% vs. 16.3%, P=0.04) specimens. No difference in the percentage of subluxation was found between the 2 groups after LCL. CT imaging demonstrated statistically significant increases in rotation between the calcaneus and cuboid after LCL in both the pinned (7.6±5.6 degrees, P=0.01) and unpinned (17±12.3 degrees, P=0.01) specimens. The degree of rotation was greater in unpinned specimens after LCL (P=0.043). CONCLUSIONS: Both sagittal and rotatory subluxation seem to occur at the CC joint after LCL regardless of pin stabilization. As a single pin would be expected to limit pure translation while having little effect on rotation, it is possible that the rotational changes identified on 3-dimensional imaging are interpreted as dorsal translation when viewed 2 dimensionally using plain radiography. Consideration should therefore be given to CC stabilization with 2 pins during LCL to prevent this rotatory subluxation. LEVEL OF EVIDENCE: Level V-cadaver study.


Posted March 16th 2021

Commentary on: Insta-Grated Plastic Surgery Residencies: 2020 Update

Robert A. Weber, M.D.

Robert A. Weber, M.D.

Morrison, S.D., Kozlow, J. and Weber, R.A. (2021). “Commentary on: Insta-Grated Plastic Surgery Residencies: 2020 Update.” Aesthet Surg J 41(3): 380-382.

Full text of this article.

In this article, Chartier et al clearly and convincingly document the rise of Instagram utilization by plastic surgery residencies since their previous publication in 2018.1,2 They also do a good job documenting the fact that most programs follow the ethical and professional guidelines that they had suggested. In fact, they did not report a single episode of a program’s improper utilization of Instagram. So why do the authors conclude that the advantages of social media (SoMe) utilization are far outweighed by the potential disadvantages? The data they present suggest the opposite.[No abstract; excerpt from article].


Posted March 16th 2021

Anxiety sensitivity, COVID-19 fear, and mental health: results from a United States population sample.

Ann M. Warren Ph.D.

Ann M. Warren Ph.D.

Warren, A.M., Zolfaghari, K., Fresnedo, M., Bennett, M., Pogue, J., Waddimba, A., Zvolensky, M., Carlbring, P. and Powers, M.B. (2021). “Anxiety sensitivity, COVID-19 fear, and mental health: results from a United States population sample.” Cogn Behav Ther Feb 17;1-13. [Epub ahead of print].

Full text of this article.

The COVID-19 pandemic has resulted in unprecedented consequences. Transdiagnostic factors, such as anxiety sensitivity, could be an important component to understand how individuals experience COVID-19 specific fear, depression and anxiety. A US representative sample (5,023) completed measures including the Anxiety Sensitivity Index-3, the Fear of COVID-19 Scale, the Generalized Anxiety Disorder-7 and the Patient Health Questionnaire-8. Analyses controlled for age, sex, race, marital status, education level, working status, household income, and COVID-19 exposure. Results were consistent with prediction. First, higher ASI-3 Total scores were associated with above average COVID-19 fear (β = 0.19). Second, the ASI-3 physical concerns subscale was the strongest predictor of COVID-19 fear; one SD increase on the ASI-3 physical concerns subscale was associated with almost a twofold risk of reaching above average levels of COVID-19 (OR = 1.93). Third, higher ASI-3 Total scores were associated with higher anxiety (β = 0.22) and depression (β = 0.20). Finally, COVID-19 fear mediated the relationship between ASI-3 Total scores and anxiety (17% of effect mediated) as well as ASI-3 Total scores and depression (16% of effect mediated). These data support the role of anxiety sensitivity in predicting fear of COVID-19 and resulting mental health.


Posted March 16th 2021

The unlimited possibilities for qualitative research in liver transplantation.

Anji Wall, M.D.

Anji Wall, M.D.

Wall, A. (2021). “The unlimited possibilities for qualitative research in liver transplantation.” Liver Transpl Feb 8. [Epub ahead of print].

Full text of this article.

As the outcomes of liver transplantation (LT) continue to improve, liver transplant recipients (LTRs) are beginning to resemble other aging, chronic disease populations.(1) This improvement in outcomes requires a shift in the focus of post-LT care from that of short-term survival to long-term chronic disease management.(2).


Posted March 16th 2021

The use of supplemental hydrocortisone in the management of persistent pulmonary hypertension of the newborn.

Veeral N. Tolia M.D.

Veeral N. Tolia M.D.

Aleem, S., Robbins, C., Murphy, B., Elliott, S., Akinyemi, C., Paredes, N., Tolia, V.N., Zimmerman, K.O., Goldberg, R.N., Benjamin, D.K. and Greenberg, R.G. (2021). “The use of supplemental hydrocortisone in the management of persistent pulmonary hypertension of the newborn.” J Perinatol Feb 15. [Epub ahead of print].

Full text of this article.

OBJECTIVE: Characterize association between hydrocortisone receipt and hospital outcomes of infants with persistent pulmonary hypertension of the newborn (PPHN). STUDY DESIGN: Cohort study of infants ≥34 weeks with PPHN who received inhaled nitric oxide at <7 days of age (2010-2016). We generated propensity scores, and performed inverse probability-weighted regression to estimate hydrocortisone effect on outcomes: death, chronic lung disease (CLD), oxygen at discharge. RESULTS: Of 2743 infants, 30% received hydrocortisone, which was associated with exposure to mechanical ventilation, sedatives, paralytics, or vasopressors (p < 0.001). There was no difference in death, CLD, or oxygen at discharge. In infants with meconium aspiration syndrome, hydrocortisone was associated with decreased oxygen at discharge (odds ratio 0.56; 95% confidence interval 0.21, 0.91). CONCLUSIONS: There was no association between hydrocortisone receipt and death, CLD, or oxygen at discharge in our cohort. Prospective studies are needed to evaluate the effectiveness of hydrocortisone in infants with PPHN.